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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of age-related macular degeneration (AMD)
ncRNA name ARMS2 siRNA
ncRNA Category siRNA
Disease name age-related macular degeneration (AMD)
Species Homo sapiens
Tissues/Cell_line human RPE cell line ARPE-19
Methods siRNA transfection, qPCR, Western blot, ELISA
Expression pattern associated
Functional description Compared with the blank control group, reduced TAI of C3, C5, IL-6, IL-8, and TNF-α were detected in the ARMS2-siRNA group.
PubMed ID 23959158
Year 2013
Title ARMS2 interference leads to decrease of proinflammatory mediators.
Drug-related ncRNA NO

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